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Hexamethonium Dichloride

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Hexamethonium Dichloride Specification

Assay
>=99%

Place of Origin
India

Particle Size
Fine powder

Melting Point
245-250C

Residue on Ignition
0.1%

Moisture (%)
0.5%

Boiling point
Not applicable (decomposes)

Storage
Store in a cool, dry place, tightly closed container

Ph Level
Neutral

Heavy Metal (%)
0.001%

EINECS No
200-468-3

HS Code
29212990

Molecular Formula
C12H30Cl2N2

Loss on Drying
0.5%

Molecular Weight
288.26 g/mol

Other Names
Hexamethonium chloride

CAS No
60-25-3

Type
Pharmaceutical Intermediates

Grade
Analytical Grade

Usage
Pharmaceutical, Laboratory chemicals, Research

Purity
99%

Appearance
Crystalline solid

Application
Ganglionic blocker, research chemical, pharmaceutical synthesis

Raw Material
Sourced from certified suppliers

Smell
Odorless

Color
White

Form
Powder

Hexamethonium Dichloride Trade Information

Main Export Market(s)
Australia, North America, South America, Middle East, Eastern Europe, Asia, Western Europe, Central America, Africa

Main Domestic Market
All India

About Hexamethonium Dichloride

Hexamethonium dichloride is a medication that was used in the past as a ganglionic blocker to lower blood pressure by inhibiting the transmission of signals between nerves in the autonomic nervous system. It was originally used as an antihypertensive agent in the treatment of high blood pressure, but it has largely been replaced by newer, more effective drugs.

Hexamethonium dichloride works by blocking the action of acetylcholine, a neurotransmitter that is involved in the transmission of nerve impulses between nerve cells in the autonomic nervous system. This blockade leads to a decrease in the activity of both the sympathetic and parasympathetic nervous systems, resulting in a decrease in blood pressure.

While hexamethonium dichloride has been largely replaced by newer drugs, it is still used in some research studies to investigate the function of the autonomic nervous system. It is also used in some clinical settings as a diagnostic tool to assess the function of the autonomic nervous system in certain disorders, such as orthostatic hypotension.

However, it is important to note that hexamethonium dichloride is a potent drug that should only be used under the supervision of a qualified healthcare professional, due to its potential for serious side effects such as low blood pressure, constipation, dry mouth, blurred vision, and urinary retention.

FAQ

1. Hexamethonium dichloride: What is it?

Ans - A quaternary ammonium salt called hexamethonium dichloride is employed as an antispasmodic and an antihypertensive medication.

2. What are Hexamethonium Dichloride's side effects?

Ans - Hexamethonium Dichloride's most frequent adverse effects include sleepiness, dizziness, dry mouth, blurred vision, and constipation.

3. How should Hexamethonium Dichloride be stored?

Ans - Keep hexamethonium dichloride at room temperature and shield it from heat, light, and moisture.

4. How much hexamethonium dichloride is advised to take?

Ans - Hexamethonium Dichloride should be taken 30-60 mg orally, two or three times a day.

5. Should I exercise any caution when using hexamethonium dichloride?

Ans - Avoiding alcohol and other drugs including antacids, antihistamines, and diuretics that might interact with hexamethonium dichloride is crucial. If you are pregnant or nursing, it's also crucial to see your doctor before using hexamethonium dichloride.

Superior Stability and Purity

Hexamethonium Dichloride offers outstanding stability and purity, with a minimum assay of 99% and a shelf life of 24 months when stored in a cool, dry place inside tightly closed containers. Its fine powder form and low moisture content (<0.5%) ensure consistent performance in laboratory and pharmaceutical environments.

Flexible Packaging and Documentation

Our product is available in sealed HDPE bottles or drums, with options for custom packaging to meet specific preferences. Each batch can be accompanied by a Certificate of Analysis upon request, validating its quality and compliance with rigorous industry standards.

Multiple Applications in Research and Pharma

Hexamethonium Dichloride serves as a ganglionic blocker in pharmaceutical synthesis, laboratory experiments, and chemical research. Its neutral pH, high purity, and reliable sourcing from certified suppliers underpin its reputation as a trusted raw material for scientists and production teams.

FAQ's of Hexamethonium Dichloride:

Q: How should Hexamethonium Dichloride be stored to maintain its stability?

A: Hexamethonium Dichloride should be stored in a tightly closed container in a cool, dry place to preserve its stability. The product remains stable when kept under these recommended storage conditions.

Q: What are the main uses of Hexamethonium Dichloride in the pharmaceutical and research sectors?

A: Hexamethonium Dichloride is primarily used as a pharmaceutical intermediate, ganglionic blocker, and research chemical. It finds application in various laboratory and synthetic processes due to its high purity and consistent properties.

Q: When will a Certificate of Analysis be available for Hexamethonium Dichloride?

A: A Certificate of Analysis for Hexamethonium Dichloride is available upon request with each batch. This document provides detailed information on the product's purity, assay, and other analytical data.

Q: Where does the manufacturing and sourcing of Hexamethonium Dichloride take place?

A: Hexamethonium Dichloride is manufactured and supplied by certified exporters and manufacturers in India, ensuring product quality and compliance with international standards.

Q: What is the process for packaging and shipping Hexamethonium Dichloride to ensure product integrity?

A: Hexamethonium Dichloride is packaged in sealed HDPE bottles or drums, with custom packaging options available. This secure packaging maintains product purity and prevents contamination during transit and storage.

Q: What benefits does Hexamethonium Dichloride provide for laboratory and pharmaceutical research?

A: Its exceptional purity, stability, and non-hazardous classification according to IATA/IMDG make Hexamethonium Dichloride highly desirable for laboratory experiments, pharmaceutical synthesis, and research applications.

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