TETRA BUTYL AMMONIUM FLUORIDE TRIHYDRATE

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TETRA BUTYL AMMONIUM FLUORIDE TRIHYDRATE

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TETRA BUTYL AMMONIUM FLUORIDE TRIHYDRATE Specification

Heavy Metal (%)
<0.001%

EINECS No
209-995-8

Assay
>98%

Boiling point
Not applicable (decomposes)

Melting Point
125-130C

Molecular Weight
261.38 g/mol

Storage
Store in tightly closed container, cool dry place

Molecular Formula
C16H36FNO3

Place of Origin
India

HS Code
29239000

Other Names
TBAF Trihydrate

CAS No
87749-50-6

Type
Chemical Reagent

Grade
Analytical / Laboratory Grade

Usage
Organic Synthesis, Phase-Transfer Catalyst, Deprotection Reagent

Purity
98%

Appearance
Crystalline solid

Application
Organic synthesis, Fluorination agent, Silica gel deprotection

Raw Material
Tetra Butyl Ammonium, Hydrogen Fluoride

Smell
Characteristic

Color
White

Form
Solid

Structure
Quaternary ammonium fluoride trihydrate

Packaging
Sealed bottle, available in various pack sizes

Solubility
Soluble in water, DMSO, DMF, MeOH

Handling Precautions
Avoid moisture and direct sunlight

Shelf Life
2 years under recommended storage

Hazard Statements
Corrosive, causes severe skin burns and eye damage

Sensitivity
Hygroscopic

UN Number
UN2922

Stability
Stable under recommended conditions

TETRA BUTYL AMMONIUM FLUORIDE TRIHYDRATE Trade Information

Main Export Market(s)
Western Europe, Central America, Asia, Australia, North America, South America, Middle East, Eastern Europe, Africa

Main Domestic Market
All India

About TETRA BUTYL AMMONIUM FLUORIDE TRIHYDRATE

The organic salt tetra butyl ammonium fluoride trihydrate (TBAF3H2O) has the chemical formula (C4H9)4NF3H2O. At ambient temperature, it is a white, crystalline solid that is frequently employed as a source of fluoride ions in a variety of chemical processes.

The quaternary ammonium salt known as TBAF is very soluble in polar organic solvents and water. It is frequently employed in organic synthesis as a moderate and selective fluorinating reagent, particularly in the deprotection of various protective groups like silyl ethers and acetals.

Additionally, the natural product and pharmaceutical TBAF has been employed in the production of Taxol, an anti-tumor agent. TBAF has also been utilised to functionalize a variety of materials, including the production of self-assembled monolayers and the alteration of carbon nanotubes.

However, due to its high alkalinity and propensity for toxicity when consumed or inhaled, TBAF can be dangerous. When handling TBAF, proper safety procedures should be followed, including the use of protective gear and sufficient ventilation.

Overall, TBAF is a helpful and adaptable reagent in organic synthesis and materials research, but due to its possible risks, care should be taken when handling it.

Superior Quality for Synthesis

Tetra Butyl Ammonium Fluoride Trihydrate offers exceptional purity and reliability, making it a preferred choice among chemists for organic synthesis. Its effectiveness as a phase-transfer catalyst allows for efficient reactions, while its solubility in common solvents ensures maximum flexibility in experimental design. Supplied in sealed bottles, it maintains integrity and performance throughout its shelf life.

Safe Handling and Storage

Being hygroscopic and corrosive, TBAF Trihydrate requires careful storage and handling. The compound must be kept in a tightly closed container, away from moisture and sunlight, to preserve its stability. Proper procedures not only protect users from skin burns and eye damage but also extend the reagent's usability, ensuring consistent results for laboratory applications.

FAQ's of TETRA BUTYL AMMONIUM FLUORIDE TRIHYDRATE:

Q: How should Tetra Butyl Ammonium Fluoride Trihydrate be stored to maintain its stability?

A: For optimal stability, store TBAF Trihydrate in a cool, dry place in a tightly sealed bottle. Avoid exposure to moisture and direct sunlight to prevent degradation and preserve its two-year shelf life.

Q: What precautions are necessary when handling TBAF Trihydrate?

A: Due to its hygroscopic and corrosive nature, always wear appropriate personal protective equipment, avoid direct skin and eye contact, and handle it in a well-ventilated area. Store the chemical away from moisture and sunlight to prevent hazardous reactions.

Q: Where can TBAF Trihydrate be applied in organic synthesis?

A: TBAF Trihydrate is commonly utilized as a phase-transfer catalyst and deprotection reagent, especially for silica gel deprotection processes and fluorination reactions, making it valuable in advanced organic synthesis workflows.

Q: What are the main benefits of using TBAF Trihydrate over other fluoride sources?

A: TBAF Trihydrate provides high purity, solubility in various solvents, and efficient catalytic properties. Its crystalline solid form promotes easy handling and accurate measurement, enhancing reliability and reproducibility in laboratory and industrial applications.

Q: When is TBAF Trihydrate typically used during the synthesis process?

A: It is mainly introduced during phase-transfer catalysis steps, deprotection phases, or when mild yet effective fluorinating agents are required, making it adaptable across multiple synthetic routes.

Q: How is TBAF Trihydrate packaged and supplied to ensure safety?

A: TBAF Trihydrate is packaged in sealed, secure bottles available in multiple pack sizes to suit laboratory demands. This packaging method helps prevent exposure to moisture and maintains reagent quality from supplier to end-user.

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